2-Methyl-4-chlorophenoxyacetic acid and bromoxynil herbicide death

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Toxicity and distribution of 2-methyl-4-chlorophenoxyacetic acid (MCPA) in developing chick embryos.

The toxicity of the herbicide Erbitox E30, a commercial formulation of 2-methyl-4-chlorophenoxyacetic acid (MCPA) containing 28% MCPA as sodium-potassium salt and 72% of unknown ingredients, was tested on chick embryos. Sterile aqueous solutions of MCPA were injected into the air chamber at doses of 0, 1.5, 3.0, 6.0, 9.0, or 10.5 mg/egg on day 0 or on day 4 of incubation. The mortality rate for...

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A fatal intoxication from ingestion of 2-methyl-4-chlorophenoxyacetic acid (MCPA).

We report a fatal intoxication case by the ingestion of an herbicide, 2-methyl-4-chlorophenoxyacetic acid (MCPA). A 23-year-old male was found dead in his car. The forensic autopsy revealed no remarkable morphological changes. However, in a toxicological screening test, MCPA was qualitatively detected from the extracts of stomach contents. Then MCPA in the extract of each body fluid and organ t...

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Chronic toxicity of 2-methyl-4-chlorophenoxyacetic acid (MCPA) in mice.

One of the phenoxy herbicides, 2-methyl-4-chlorophenoxyacetic acid (MCPA) was soaked with pellet dissolved by corn oil and given to ICR male mice for 18 months at levels of 40, 200, 1,000 and 5,000 ppm (about 3.9, 19.0, 95.6 and 566.4 mg/kg/day, respectively). The animals were then placed on a control diet for 12 months. Treatment with 5,000 ppm of MCPA resulted in a significantly decreased sur...

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The title compound, C(10)H(11)NO(4)S, is of inter-est with respect to its biological activity. The mol-ecules are linked into centrosymmetric dimers by inter-molecular O-H⋯O hydrogen bonds and the dimers are further connected into chains by weak C-H⋯O inter-actions.

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In the title compound, C(12)H(16)N(2)O(6)S, the S atom adopts a distorted tetra-hedral geometry with an O-S-O angle of 119.76 (13)°. The nitro group is twisted by 35.34 (2)° with respect to the aromatic ring; it accepts an N-H⋯O hydrogen bond, resulting in a S(7) motif. In the crystal, N-H⋯O and O-H⋯O hydrogen bonds connect the mol-ecules into an infinite chain along the a axis. The methyl C at...

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ژورنال

عنوان ژورنال: Clinical Toxicology

سال: 2015

ISSN: 1556-3650,1556-9519

DOI: 10.3109/15563650.2015.1030025